We examined the relationship between continental-level genetic ancestry and racial and ethnic identity in an admixed population in New Mexico with the goal of increasing our understanding of how racial and ethnic identity influence genetic substructure in admixed populations.Our sample consists of 98 New Mexicans who self-identified as Hispanic or
Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD).It is unclear how changes to TDP-43, including nuclear to cytosolic translocation and subsequent accumulation, are controlled in these diseas
Abstract Intratumor heterogeneity of tumor clones and an immunosuppressive microenvironment in cancer ecosystems contribute to inherent difficulties for tumor treatment.Recently, chimeric antigen receptor (CAR) T-cell therapy has been successfully applied in the treatment of B-cell malignancies, underscoring its great potential in antitumor therapy
Background: This study aimed to validate the Persian version of Maslach Burnout Inventory for Medical Personnel (MBI-HSS-MP), an instrument developed to capture burnout for health professionals.The specific aims were to psychometrically assess the Persian MBI-HSS-MP in relation to its structure, test-retest reliability, and item properties.Methods: